Following the Phyto Shape debate and suggestion that contains some 40-45 mg of Reductil, we did some search and found useful information from one UK source:Reductil capsules contain the active ingredient sibutramine hydrochloride monohydrate, which is a type of anti-obesity medicine. It works by affecting neurotransmitters in the brain.
Neurotransmitters are natural body chemicals that are stored in nerve cells and are involved in transmitting messages between the nerve cells. They are released from nerve cells as a message is transmitted. Once the message has been transmitted, the nerve cells then reabsorb the neurotransmitter.
Sibutramine prevents two of these neurotransmitters, noradrenaline and serotonin, from being reabsorbed back into the nerve cells. Noradrenaline and serotonin are responsible for moderating mood and various other processes in the brain. The sibutramine helps people to lose weight by increasing the amount of noradrenaline and serotonin free to act in the brain. This enhances the feeling of fulfillment from eating, and so makes you feel satisfied after eating less food.
You will need to continue with an appropriate diet and exercise programme while taking this medicine, so that you are able to maintain your new weight after you have stopped treatment. Your doctor should give you advice to assist you with this.
Neurotransmitters are natural body chemicals that are stored in nerve cells and are involved in transmitting messages between the nerve cells. They are released from nerve cells as a message is transmitted. Once the message has been transmitted, the nerve cells then reabsorb the neurotransmitter.
Sibutramine prevents two of these neurotransmitters, noradrenaline and serotonin, from being reabsorbed back into the nerve cells. Noradrenaline and serotonin are responsible for moderating mood and various other processes in the brain. The sibutramine helps people to lose weight by increasing the amount of noradrenaline and serotonin free to act in the brain. This enhances the feeling of fulfillment from eating, and so makes you feel satisfied after eating less food.
You will need to continue with an appropriate diet and exercise programme while taking this medicine, so that you are able to maintain your new weight after you have stopped treatment. Your doctor should give you advice to assist you with this.
Apparently Reductil is not a new drug and despite any site effects is freely sold around the world. The UAE daily Khaleej Times published that the Ministry of Health has withdrawn the Phyto Shape from the local market.
5 comments:
Hi girls,
The Reductil is not a new drug. I tried about 2 years ago in combination with Xenical. At that time I lost about 10 kg in three months. These drugs should be prescribed by your doctor and you have to be very careful as they are not side effects free. It's not something I would recommend however.
And yes, you can buy Reductil in Dubai.
xx
Here is how the both work together:
Xenical stops around 30 percent of the fat you’ve eaten from being absorbed. It simply passes through your digestive system and you lose weight as a result.
Reductil blocks the nerve cells that release and reabsorb serotonin. This means serotonin levels increase. These act in the brain and enhance feelings of fullness so that you eat less and consequently lose weight.
You should also follow a reduced-calorie diet where no more than 30 percent of calories come from fat.
Exercise is a must.
So as you see, there is no miracle.
April/2006 Weight & DietsPermalink
Diet tablet linked to heart case
29 April 2006
By KAMALA HAYMAN
Fresh warnings are being issued about a diet pill used by more than 17,000 New Zealanders after a 40-year-old woman collapsed with a heart attack.
Otago University's Intensive Medicines Monitoring Programme (IMMP) is urging caution after uncovering the case of an Auckland mother who suffered a cardiac arrest just 25 days after starting to take the slimming pill Reductil (sibutramine).
A further five patients experienced heart palpitations, according to the study, which was published in this month's British Journal of Clinical Pharmacology.
The new research is the first in the world to report a link between the drug and abnormal heart rhythms. It has prompted action by drug authority Medsafe and calls for caution from GPs.
It also follows a warning from the associate director of the United States Federal Drugs Authority that Reductil is one of five drugs on the market that may be endangering patients.
Reductil first became available in New Zealand in 2001 and within three years had been taken by 17,000 people, each paying between $160 and $200 a month.
The patient at the centre of the latest study was an Auckland trainee nurse whose husband, finding her unconscious and without a pulse, resuscitated her. She was rushed to hospital, where it was found she had an undiagnosed genetic heart condition known as long QT syndrome.
The slimming pill, coupled with her genetic condition, had proved a near-fatal combination.
The woman's GP, Angela Konings, of Mairangi Bay, Auckland, said her patient was lucky to be alive.
She now warned patients about the risk of Reductil in those with an abnormal heart rhythm.
Long QT syndrome is an abnormal beating of the heart and kills an estimated 80 New Zealanders a year.
However, few know they have it and it can be difficult to detect, even with an electrocardiogram. Diagnosis can be confirmed only through a genetic test.
Auckland cardiologist and long-QT expert Jonathan Skinner, co-author of the latest study, said the patient had a normal ECG before taking Reductil. Within a month, she had a cardiac arrest.
"It might be a coincidence, but it does seem rather extraordinary," he said.
IMMP director Mira Harrison-Woolrych said Reductil could prove fatal in those with long QT syndrome. "But people often don't know they have long QT, and that's the difficulty."
The IMMP has previously reported an apparent link between Reductil and memory loss and bruising.
Christchurch GP and School of Medicine researcher Les Toop said Reductil should be prescribed only for the obese.
"One doctor had a stand-up row with a patient who was not obese but demanded Reductil because she needed to drop two dress sizes for a wedding," he said.
Fellow GP and researcher Dee Mangin called for all patients to be given an ECG before starting Reductil.
"It should be prescribed only after careful consideration of the risks and benefits in that patient.
"There are 18 contra-indications for taking this drug."
Medsafe spokesman Stewart Jessamine said Medsafe had requested the drug's data sheet carry a new warning "stating that rare cases of heart-rhythm abnormalities have been reported" and the drug should be avoided in anyone with known or suspected heart-rhythm problems.
Patients were already required to have their pulse and blood pressure measured every two weeks for the first three months of treatment on Reductil.
However, Jessamine said heart-rhythm abnormalities "are likely to occur very rarely" in Reductil patients, and, for the majority, the risks of the drug remained unchanged.
Drug manufacturer Abbott Australasia said Reductil had been studied in more than 100 global clinical trials involving more than 12,000 patients and been used by about 15 million patients in more than 75 countries.
In New Zealand, adverse reactions such as memory impairment and bruising had been previously noted, but the company had not found a link to QT prolongation.
It said obesity was a major risk factor for the development of many serious medical conditions, including high blood pressure, diabetes, heart disease, and stroke.
http://www.newtotalwellness.com/page2/files/archive-0.html
Hi everybody,
the Reductil is well known within the slimming society. Claims for dangerous side effects have been raised long ago in the US. But the heroin is also very popular and still is sold and many youts are dependent and victims are dying daily. Guess this is how business is done all over the world................sadly!
Reductil contains sibutramine as an active ingredient, which is an appetite suppressant. It helps to increase levels of neurotransmitters, serotonin and noradrenaline, that act in hypothalamus part of the brain. Sibutramine in Reductil can lead to suppression of appetite. People lose weight because of this action that targets appetite and they eat less food.
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